Get turn-by-turn directions
One enduring Google Android advantage over iOS has been its turn-by-turn navigation feature -- ironic, since Apple used Google's Map apps to deliver directions. Apple has dumped Google Maps (as well as the Google-owned YouTube app) from iOS 6 and delivered its own version.
On an iPhone 4S or later or on a third-gen iPad, that Maps app delivers turn-by-turn navigation, with the option of spoken instructions. Sadly, earlier devices don't get this capability, so you'll need an app like Navigon or TeleNav instead.